Anti-Lamin B2 Antibody

This unconjugated polyclonal reagent from Antibodies.com targets Lamin B2, a type V intermediate filament protein that anchors the inner nuclear membrane and organizes peripheral chromatin. Raised in rabbit and supplied as a 100 µl liquid aliquot in a single-use vial, the antibody is validated for western blot and immunohistochemistry on human specimens, producing the expected ~68 kDa band by WB and crisp perinuclear staining on fixed tissue sections.

Lamin B2 (encoded by LMNB2) is a broadly used structural marker of nuclear envelope integrity, and investigators employ this antibody to monitor nuclear morphology during differentiation, mitotic exit, senescence, and apoptotic breakdown. Because the reagent is unconjugated, users can pair it with their preferred secondary antibody for chromogenic IHC, immunofluorescence, or chemiluminescent western blot workflows. Store refrigerated in the original vial between uses and minimize freeze-thaw cycles to preserve antibody activity.