Anti-Lamin B1 Antibody

Manufactured by Antibodies.com as part of their primary antibody portfolio, this affinity-purified reagent is raised in rabbit and is polyclonal, targeting endogenous Lamin B1 with high specificity. The immunogen is a synthesized peptide derived from the N-terminal region of human Lamin B1, and the antibody is supplied unconjugated at a concentration of 1 mg/mL in a 50 µL liquid format buffered in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide. Validated for use in ELISA, Western Blot (WB), and Immunohistochemistry (IHC), the reagent reacts with human, mouse, and rat samples and is widely employed as a nuclear envelope marker and as a loading control for nuclear fractions. Purification is carried out by affinity chromatography from rabbit antiserum using the epitope-specific immunogen, ensuring clean detection of the Lamin B1 protein in a variety of sample types. Each unit is shipped at 4°C, with the recommendation to aliquot upon arrival and store at -20°C while avoiding repeated freeze/thaw cycles to preserve antibody integrity. The product is intended for research use only and is not for diagnostic or therapeutic applications. Known gene and protein aliases recognized by this reagent include LMN2, LMNB, and LMNB1, reflecting its broad utility across commonly studied mammalian model systems.