Anti-Lamin B1 Antibody

Offered through the Antibodies.com catalogue of primary antibodies, this mouse monoclonal reagent targets Lamin B1 (LMNB1), a key intermediate-filament protein of the nuclear envelope. The antibody is supplied at a concentration of 1 mg/mL in a 50 µL volume, formulated in PBS (pH 7.4) with 0.02% sodium azide as preservative and 50% glycerol for stability, and it has been affinity-purified from antiserum by affinity chromatography to ensure clean detection of native Lamin B1 protein in Human, mouse, and rat samples. Because the reagent is unconjugated, it is well suited to standard immunodetection workflows, with validated applications including Western blot (WB) and immunoprecipitation (IP), making it a flexible choice for studies of nuclear architecture, chromatin organisation, and lamin-associated disease models. Produced in mouse as a monoclonal antibody, the clone provides batch-to-batch consistency and reproducible signal across blots and pull-down assays, and it recognises endogenous Lamin B1 without the need for exogenous over-expression in most cell systems. Designed for research use only, the reagent is intended to support routine characterisation of nuclear envelope integrity in cell lysates and tissue extracts, and is recommended for laboratories working on comparative studies across human and rodent species where cross-reactivity with Human, Rat, and Mouse Lamin B1 is required.