Anti-Lamin A/C (S17) Antibody

This rabbit polyclonal antibody from Antibodies.com recognizes Lamin A and Lamin C, the intermediate filament proteins that assemble into the nuclear lamina meshwork supporting the inner nuclear membrane. Researchers apply it to western blot and immunohistochemistry workflows investigating nuclear envelope integrity, laminopathy mechanisms such as Hutchinson-Gilford progeria, and apoptosis-associated lamin processing events. The reagent reacts with human, mouse, and rat samples, and the unconjugated format leaves secondary labeling chemistry to the researcher's preferred detection system.

Each vial contains 100 µl at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, ready to aliquot into working stocks. Store refrigerated between uses and protect from light to preserve binding activity over the shelf life of the reagent. The polyclonal response targets multiple epitopes on Lamin A/C, which improves tolerance for variation across sample preparation conditions and helps reveal both full-length and processed forms in cell and tissue extracts.