Anti-LAMC3 Antibody

Raised in rabbit and supplied as an unconjugated polyclonal reagent, this 100 µl antibody targets LAMC3, the gamma-3 chain of the basement membrane glycoprotein laminin. Manufactured by Antibodies.com, it is validated for Western blot, immunohistochemistry, and immunofluorescence, and recognizes the human and mouse protein in tissue sections and cell preparations. Researchers investigating cortical development, neuronal migration, and extracellular matrix biology use it to map laminin distribution at the pial surface, where LAMC3 expression has been linked to occipital encephalocele and polymicrogyria. The polyclonal format yields recognition of multiple epitopes on the gamma-3 subunit, which is useful when probing fixed samples or denatured lysates where conformational epitopes may be lost.