Anti-LAMB3 Antibody

This rabbit-derived polyclonal reagent from Antibodies.com targets Laminin subunit beta-3 (LAMB3), a basement membrane glycoprotein expressed in stratified epithelia. The unconjugated IgG antibody is supplied at 200 µl and validated for immunohistochemistry (IHC) on human tissue sections. LAMB3 contributes to hemidesmosome assembly and laminin-332 architecture, and loss-of-function mutations are linked to junctional epidermolysis bullosa, making this reagent useful for studies of epithelial adhesion, skin blistering disorders, and tumor basement membrane biology. Researchers can apply it to formalin-fixed paraffin-embedded sections to map laminin distribution in skin, oral mucosa, and other epithelial interfaces, supporting investigations into wound healing, keratinocyte differentiation, and carcinoma invasion patterns.