Anti-LAMA4 Antibody

This rabbit polyclonal antibody from Antibodies.com targets the laminin subunit alpha-4 (LAMA4) protein, a key component of basement membranes that contributes to extracellular matrix organization, cell adhesion signaling, and tissue structural integrity across epithelial and endothelial compartments. LAMA4 has been studied in the context of cardiovascular development, where it modulates cardiomyocyte adhesion and vascular smooth muscle behavior, and in oncology research, where altered laminin expression influences tumor cell migration, basement membrane remodeling, and angiogenic signaling. The reagent is supplied as 100 µl of unconjugated IgG in liquid format, raised in rabbit, and validated for western blot detection of the human LAMA4 target. Researchers commonly apply this antibody to lysates derived from human cell lines and tissue samples to investigate LAMA4 protein expression under normal physiological conditions and in disease models such as dilated cardiomyopathy and certain epithelial-derived carcinomas. The polyclonal format supports recognition of multiple epitopes on the laminin alpha-4 chain, which can be advantageous for detecting the protein across denatured and reduced western blot conditions. This unconjugated primary antibody is intended for research use only, allowing investigators to pair it with secondary reagents matched to their preferred detection chemistry.