Anti-KV4.2 Antibody

Generated in rabbit as a polyclonal reagent, this Antibodies.com antibody targets the KV4.2 voltage-gated potassium channel (KCND2), a Shal-family subunit that shapes somatodendritic A-type currents and dendritic signal integration in hippocampal and cortical neurons. The unconjugated IgG is supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol as a cryoprotectant, shipped as 100 µl in a single vial that is typically aliquoted to limit freeze-thaw cycles and stored refrigerated for short-term use or frozen at -20 °C for longer-term stability. Validated on Human, Mouse, and Rat samples, the antibody supports western blot detection of the expected ~70 kDa band and immunohistochemical labeling of neuronal soma and dendrites, making it useful for studies of channel subunit trafficking, subcellular localization, and remodeling in models of epilepsy, neuropathic pain, and synaptic plasticity.