Anti-Kv4.1 (N588) Antibody

Supplied by Antibodies.com, this rabbit polyclonal primary antibody targets the Kv4.1 voltage-gated potassium channel subunit (KCND1) at the N588 region and is raised against a synthetic peptide corresponding to amino acids 559–610 of the human protein. The reagent is provided as 50 µl of affinity-purified IgG at approximately 1 mg/ml, formulated in phosphate-buffered saline (PBS, pH ~7.2) with 0.05% sodium azide as a preservative. Host species is rabbit, clonality is polyclonal, isotype is IgG, and the conjugate is unconjugated, making the antibody suitable for use with secondary detection systems of the researcher's choice. Validated applications include Western blotting (WB) and immunohistochemistry (IHC), and the antibody has been confirmed to react with both human and mouse samples. Recommended working dilutions are 1:500–1:1000 for WB and 1:50–1:200 for IHC on paraffin-embedded sections, where it has been demonstrated on human breast carcinoma tissue. For routine storage, the supplier recommends keeping the vial at –20 °C for long-term use, with short-term storage at 4 °C for up to one month, while avoiding repeated freeze-thaw cycles to preserve antibody activity. This product is part of the Antibodies.com Primary Antibodies range and is intended for research use, offering reliable detection of the Kv4.1 channel in studies of neuronal and cardiac excitability, A-type potassium currents, and related signalling pathways.