Anti-Ku70 Antibody

A mouse monoclonal IgG1 antibody that specifically recognizes the Ku70 protein, a 70 kDa subunit of the Ku heterodimer (Ku70/Ku80) that binds DNA double-strand breaks and initiates non-homologous end joining repair. Supplied by Antibodies.com as an unconjugated reagent in a 100 µl vial, this reagent is validated for Western blot, immunocytochemistry, and immunoprecipitation workflows. It cross-reacts with human and monkey (primate) samples, supporting comparative studies of DNA damage response, telomere maintenance, and V(D)J recombination mechanisms in mammalian cell systems. The IgG1 isotype permits pairing with standard secondary antibodies, while the unconjugated format offers flexibility for direct labeling or signal amplification strategies in cell biology and cancer research applications.