Anti-Ku-70 Antibody

Raised in rabbit against the 70 kDa subunit of the Ku heterodimer, this unconjugated primary antibody from Antibodies.com is supplied as 100 µL of polyclonal antiserum in a vial and is validated for western blot and ELISA workflows. Ku70 partners with Ku80 to form the DNA-binding component of the DNA-dependent protein kinase complex, acting in non-homologous end joining to repair double-strand DNA breaks and contributing to telomere capping at chromosome ends. The reagent is reactive against human, mouse, and rat samples, enabling comparative studies of DNA damage response, genomic stability, and apoptosis in standard laboratory systems. Because it is unconjugated, it pairs with HRP- or fluorophore-labeled secondary reagents for chemiluminescent western blot readouts or plate-based detection. For handling, refrigerate the vial upon arrival, aliquot to limit freeze-thaw cycles, and protect from light to preserve activity across the shelf life of the reagent.