Anti-KRT4 Antibody - Identical to Abcam (ab197385)

This unconjugated rabbit polyclonal IgG antibody recognizes cytokeratin 4 (KRT4), a type II keratin expressed in differentiated mucosal and non-keratinizing stratified squamous epithelia. Manufactured by Antibodies.com, the reagent is supplied as 50 µl of liquid antiserum and is validated specifically for Western blot (WB) use on human, mouse, and rat samples for research use only.

KRT4 is co-expressed with its complementary partner KRT13 in tissues such as the oral mucosa, esophagus, and conjunctiva, where it serves as a differentiation marker for suprabasal epithelial cells. Investigators studying mucosal biology, oral cancer models, esophageal pathology, and white sponge nevus (a condition arising from KRT4 mutations) commonly apply this reagent to confirm target expression. The polyclonal, unconjugated format allows flexible pairing with HRP, fluorescent, or biotinylated secondary antibodies within the chosen Western blot detection workflow, including standard reducing SDS-PAGE analysis of cell and tissue lysates.