Anti-KRT4 Antibody

Keratin 4 (KRT4) is a type II cytokeratin predominantly expressed in mucosal and non-keratinizing stratified squamous epithelia, including the oral cavity, esophagus, and conjunctiva. This polyclonal antibody from Antibodies.com, raised in rabbit, targets human KRT4 and is validated for Western blot and immunohistochemistry workflows.

Researchers apply it to investigate epithelial differentiation, mucosal barrier integrity, and disorders linked to KRT4 dysfunction, notably White Sponge Nevus, a benign oral leukokeratosis associated with mutations in the KRT4 gene. The unconjugated format allows flexible pairing with custom secondary detection reagents, and the 100 µl volume supports multiple experimental setups.

Its confirmed reactivity with human samples makes it a useful reagent for oral pathology research, esophageal epithelial studies, and broader investigations of stratified squamous epithelial biology.