Anti-KRT19 Antibody

This rabbit polyclonal reagent from Antibodies.com targets cytokeratin 19 (KRT19), a type I intermediate filament protein widely expressed in simple and stratified epithelia. Supplied as 100 µl of unconjugated antiserum, the antibody is validated for Western blot and immunohistochemistry workflows on human and mouse samples for research use only.

KRT19 is a frequently used epithelial marker in tumor pathology, where its expression helps distinguish carcinoma-derived cells from mesenchymal or lymphoid lineages, and it is also employed to detect circulating tumor cells in research assays. Because the antibody is unconjugated, investigators can pair it with HRP-, biotin-, or fluorophore-labeled secondary reagents of their choice, making it a flexible primary reagent for both chromogenic IHC and immunoblotting membranes.

The polyclonal format increases the likelihood of recognizing multiple epitopes along the keratin filament, which can improve signal when working with formalin-fixed paraffin-embedded tissue sections. For long-term use, aliquot the contents and store refrigerated to minimize freeze-thaw damage and preserve antibody activity.