Anti-KRT17 Antibody [Assigned #A10942]

Keratin 17 (KRT17) is a type I intermediate filament protein with a predicted molecular weight of approximately 46 kDa, normally expressed in the basal cells of complex epithelia, hair follicles, and related epidermal appendages. This unconjugated rabbit monoclonal IgG reagent from Antibodies.com is supplied as a 50 µl liquid aliquot in a single vial and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples.

Research teams use this antibody to investigate epithelial differentiation, wound healing, and tumor pathology. In immunohistochemistry, KRT17 staining distinguishes basal-like and squamous phenotypes in head and neck, breast, and skin lesions, and helps separate myoepithelial cells from luminal epithelium in mammary, sweat, and salivary glands. Published studies have also linked KRT17 expression to limbal stem cell regulation in the corneal epithelium and to aggressive behavior in triple-negative breast carcinoma. The unconjugated format allows laboratories to couple the antibody to a chosen reporter, including HRP, biotin, or fluorophore conjugates, for flexibility across varied assay platforms and detection chemistries.

Each vial should be aliquoted on first use to preserve antibody activity across multiple freeze-thaw cycles. For research use only, the reagent is not intended for diagnostic or therapeutic applications.