Anti-KRT17 Antibody [Assigned #A10942]

Keratin 17 (KRT17) is a type I intermediate filament protein expressed in basal epithelial cells of the epidermis, hair follicles, and nail beds, and this rabbit monoclonal antibody from Antibodies.com provides a specific research reagent for its detection in tissue sections and cell preparations.

Supplied as a 200 µl liquid aliquot in unconjugated IgG format, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence workflows. Cross-reactivity with human, mouse, and rat samples supports comparative studies across standard model systems. For handling, store refrigerated at 4 °C for short-term use or aliquot and freeze at -20 °C for longer term storage, minimizing freeze-thaw cycles to preserve binding activity.

Investigators apply this reagent to research on epithelial proliferation, wound healing, and keratinocyte differentiation, where KRT17 serves as a marker of hyperproliferative or stressed epithelial states. Published studies cite use of this antibody on psoriasis lesions, basal cell carcinoma, and squamous cell carcinoma specimens, where it helps delineate tumor margins and characterize disease subtypes.