Anti-KRT16 Antibody

Stratified epithelia and hyperproliferative skin disorders can be investigated using this polyclonal rabbit anti-KRT16 reagent from Antibodies.com, which targets the type I intermediate filament protein Keratin 16. Keratin 16 expression is normally confined to suprabasal layers of stratified epithelia but rises sharply in wound-edge keratinocytes and psoriatic lesions, and germline mutations in KRT16 underlie focal pachyonychia congenita, making the antigen a useful marker for studies of epidermal differentiation, barrier repair, and genotype-phenotype work on keratin disorders. Supplied as a 100 µL vial of unconjugated IgG, the antibody is validated for Western blot and immunohistochemistry, supporting protein-level detection in cell or tissue lysates as well as localization in fixed paraffin sections or cryosections. The reagent reacts with human, mouse, and rat samples and is intended for research use only; short-term storage refrigerated is recommended, with longer-term aliquots kept frozen to preserve activity across multiple experiments.