Anti-KRT14 Antibody

Epithelial tissue research depends on cytokeratin markers to map basal cell populations and resolve the architecture of stratified squamous surfaces. KRT14 (Keratin 14), a type I intermediate filament protein that pairs with Keratin 5 in basal keratinocytes, is one such anchor marker. Antibodies.com supplies a rabbit-derived polyclonal antibody against this target, delivered as an unconjugated IgG preparation in a 100 µl volume.

The reagent supports three research applications: Western blot detection in protein lysates, immunohistochemistry on formalin-fixed paraffin-embedded tissue sections to visualize basal-layer distribution, and flow cytometry analysis of dissociated epithelial cell populations. Validated reactivity against human, mouse, and rat samples enables comparative work in skin, oral mucosal, and esophageal epithelial biology.

Because the antibody is unconjugated, laboratories can couple it to HRP, biotin, Alexa Fluor, or other reporters through standard secondary detection chemistries. This format flexibility supports both chromogenic immunostaining of tissue sections and multicolor flow cytometry panels. The reagent provides a foundation for investigations of inherited keratin disorders, basal-cell carcinoma biology, wound re-epithelialization, and stem-cell niches within stratified epithelia.