Anti-KRT14 Antibody

Raised in rabbit against the type I cytokeratin Keratin 14 (KRT14), this unconjugated polyclonal IgG antibody from Antibodies.com is supplied as a 50 µl volume and validated for Western blot and immunohistochemistry on human and mouse samples. KRT14 is expressed in the basal layer of stratified squamous epithelia, including the epidermis, hair follicles, and tonsillar epithelium, where it forms heterodimers with the type II keratin KRT5 to build the intermediate filament cytoskeleton of proliferating basal keratinocytes.

The reagent is widely used in dermatology and stem-cell research as a marker of epithelial basal cells and of limbal or mammary progenitor populations, and in tumor pathology to confirm squamous or basal-type differentiation in epithelial neoplasms. For handling, store aliquots refrigerated and protect from light to preserve activity across multiple freeze-thaw cycles, and centrifuge briefly before use.

The host species is rabbit, the clonality is polyclonal, the isotype is IgG, and the product is intended for research use only in laboratory workflows investigating epithelial differentiation, keratinopathies such as epidermolysis bullosa simplex, and related cell biology studies.