Anti-KRT14 Antibody

Used to identify basal keratinocytes in stratified squamous epithelia, this Rabbit polyclonal Anti-KRT14 antibody from Antibodies.com is supplied as an unconjugated IgG reagent in a 200 µl volume, raised in rabbit and validated for Western blot (WB) and immunohistochemistry (IHC) workflows.

It detects Keratin 14 (KRT14), a type I cytokeratin that pairs with KRT5 to build the intermediate filament cytoskeleton anchoring basal cells of the epidermis, oral mucosa, esophagus, and cornea to the underlying basement membrane. The reagent reacts with both Human and Mouse KRT14, enabling parallel work on patient specimens and rodent models of skin disease.

Common applications include tracking wound re-epithelialization, characterizing basal-cell and squamous-cell carcinoma pathology, and studying inherited blistering conditions such as epidermolysis bullosa simplex, a disorder caused by mutations in the KRT14 gene. Aliquot the 200 µl volume to limit freeze-thaw cycles and preserve antibody activity across multiple experiments.