Anti-KPNA1 Antibody

Raised in rabbit against the human KPNA1 nuclear import receptor, this unconjugated polyclonal antibody from Antibodies.com supports western blot, immunohistochemistry, and immunofluorescence workflows. KPNA1 (karyopherin subunit alpha 1, also called importin alpha 5) recognizes classical nuclear localization signals and mediates cargo translocation through the nuclear pore, with documented roles in signal transduction, viral nuclear delivery, and tumor biology.

The reagent is supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial. The antibody cross-reacts with mouse and rat orthologues in addition to human samples. Aliquoting is recommended to limit freeze-thaw cycles, and the buffer formulation keeps the preparation stable for routine refrigerated storage. Researchers commonly apply this reagent to investigate nucleocytoplasmic transport, NLS-dependent cargo recognition, and KPNA1 expression patterns in cultured cells and paraffin-embedded tissue sections.