Anti-KLKB1 Antibody

Plasma kallikrein, the serine protease encoded by KLKB1, drives contact activation of the intrinsic coagulation cascade and kinin release during inflammation. This unconjugated rabbit polyclonal reagent, validated for western blot, immunohistochemistry, and immunofluorescence on human samples, enables researchers to track pro-kallikrein and activated kallikrein in cell lysates, plasma fractions, and fixed tissue sections.

KLKB1 sits at the intersection of thrombosis research, hereditary angioedema biology, diabetic retinopathy, and innate immunity studies, where altered plasma kallikrein activity contributes to vascular leakage and bradykinin-mediated inflammatory signaling. The polyclonal format recognizes multiple epitopes across the heavy and light chains of the protease, supporting flexible detection under denaturing and native conditions. Each vial is supplied at 100 µl and should be aliquoted upon arrival to limit freeze-thaw cycles; storage at -20°C preserves long-term stability, and protection from light is recommended. Provided by Antibodies.com for research-use-only laboratory investigation.