Anti-KLK7 Antibody

Kallikrein-related peptidase 7 (KLK7) is a secreted chymotrypsin-like serine protease best known for its role in stratum corneum desquamation, where it cleaves corneodesmosomal cadherins. Beyond skin homeostasis, KLK7 expression is dysregulated in several malignancies, including ovarian, breast, and pancreatic cancers, where elevated levels correlate with tumor aggressiveness and metastasis. This rabbit polyclonal reagent from Antibodies.com is raised against KLK7 and validated for Western blot and immunohistochemistry on human samples, supplied as 100 µl of unconjugated antiserum suitable for chromogenic and fluorescence-based detection workflows. Researchers commonly deploy it to map KLK7 localization in tissue sections, confirm proteomic findings, or probe KLK7 processing and activity in cell-based models. Polyclonal formatting offers broader epitope coverage than monoclonal alternatives, which is helpful when tracking both pro- and mature forms of the enzyme.