Anti-KLHL3 Antibody

Supplied by Antibodies.com, this rabbit polyclonal antibody targets KLHL3 (Kelch-like protein 3) and is raised against a synthesized peptide derived from the N-terminal region of human KLHL3, allowing detection of endogenous levels of the total KLHL3 protein. The reagent is provided as an unconjugated IgG purified from rabbit antiserum by affinity chromatography against the epitope-specific immunogen, and the host species is Rabbit, with a polyclonal clonality suitable for a broad recognition of multiple KLHL3 epitopes. The 50 µL vial is formulated at 1.0 mg/mL in phosphate-buffered saline (without Mg²⁺ or Ca²⁺), pH 7.4, containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol as a cryoprotectant, and it should be stored long-term at –20 °C to preserve activity across multiple freeze-thaw cycles. In validated applications, the antibody performs reliably in Western blot (WB), immunohistochemistry (IHC) and immunofluorescence (ICC/IF), and cross-reactivity has been confirmed in Human and Mouse samples, making it a practical choice for studies involving renal ion-transport regulation, pseudohypoaldosteronism type II models and broader investigations of Cullin-3–KLHL3 E3 ligase biology. Conceived for research use only and not for diagnostic or therapeutic applications, this reagent fits neatly into the Antibodies.com portfolio of validated, application-specific primary antibodies and offers dependable lot-to-lot consistency at a working concentration that supports both standard and high-sensitivity detection protocols.