Anti-KKIALRE Antibody

Raised in rabbit and supplied at 100 µl, this unconjugated polyclonal antibody from Antibodies.com binds the KKIALRE kinase, also known as cyclin-dependent kinase-like 5, a serine/threonine kinase linked to X-linked neurodevelopmental disorders including atypical Rett syndrome and early-infantile epileptic encephalopathy.

The reagent is validated for Western blot, immunohistochemistry, and ELISA applications on human and rat samples. Its polyclonal format allows simultaneous recognition of multiple epitopes on the target protein, which can be useful when probing isoforms, post-translational modifications, or truncated variants expressed from disease-associated alleles.

KKIALRE is broadly expressed in the central nervous system, with reported roles in neuronal migration, dendritic arborization, axon outgrowth, and synaptic function. The antibody is therefore well suited to neuroscience, cell signaling, and rare-disease research workflows, supporting studies of kinase activity and subcellular localization in brain tissue and relevant cell models.