Anti-KISS1 Antibody

The Antibodies.com polyclonal reagent targets the KISS1 protein, a tumour metastasis suppressor originally identified in human melanoma cells. KISS1 encodes the kisspeptin peptide family, which signals through the GPR54 receptor (also called KISS1R) to regulate the hypothalamic-pituitary-gonadal axis, puberty onset, and gonadotropin release. Research teams studying reproductive neuroendocrinology, placental biology, and tumour spread use this reagent to investigate kisspeptin expression in tissue sections and cell lysates.

Raised in rabbit, the unconjugated IgG is supplied as 100 µl of polyclonal antiserum for Western blot and immunohistochemistry workflows. The antibody has been validated for reactivity with human and mouse samples, making it useful for translational projects that compare kisspeptin distribution across species or that link expression changes to disease models of hypothalamic dysfunction, gestational disorders, and metastatic progression. Protect from light, aliquot to limit freeze-thaw cycles, and handle on ice for short-term bench use. The polyclonal format offers broader epitope coverage than a monoclonal clone, which can be advantageous when mapping variant expression or detecting processed kisspeptin fragments in fixed or frozen specimens.