Anti-KIR3DL1 Antibody

KIR3DL1 (Killer-cell immunoglobulin-like receptor 3DL1) is a key inhibitory receptor expressed on natural killer (NK) cells and subsets of T lymphocytes, where it surveys HLA class I molecules on target cells to regulate cytotoxic responses.

This unconjugated rabbit polyclonal reagent from Antibodies.com is supplied at 50 µL volume, validated for western blot (WB) and immunohistochemistry (IHC) workflows on human samples.

Researchers investigating transplant tolerance, viral immunity, and tumor immune evasion frequently use anti-KIR3DL1 antibodies to characterize NK cell repertoire diversity and to profile HLA-B allotype interactions. The polyclonal format increases the likelihood of recognizing multiple epitopes across the receptor's extracellular immunoglobulin domains, which can be useful when distinguishing closely related KIR family members or detecting low-abundance receptor expression in tissue sections.