Anti-KIR3DL1 Antibody

This polyclonal antibody from Antibodies.com targets the KIR3DL1 receptor, a member of the killer cell immunoglobulin-like receptor family expressed primarily on natural killer (NK) cells and a subset of cytotoxic T lymphocytes. Raised in rabbit, the reagent is supplied at 1 mg/mL in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, and is unconjugated for flexibility in downstream detection chemistries. The 100 µL pack size is validated for Western blot and immunohistochemistry workflows and has been confirmed reactive with human and mouse samples, supporting translational studies that span tissue-based tumor immunology investigations and cell-line or primary-cell characterization. Researchers commonly apply this reagent to map HLA-Bw4-mediated NK inhibition in the context of infectious disease, transplantation, and cancer immunotherapy research, where KIR3DL1 expression is studied as a biomarker of NK cell education and functional licensing. Aliquoting upon first use is recommended to minimize freeze-thaw cycles, and the glycerol-containing formulation permits storage at -20 °C for stable activity over extended periods.