Anti-KIR2DL1 Antibody

Rabbit polyclonal antibody targeting KIR2DL1, a member of the killer cell immunoglobulin-like receptor family expressed on natural killer (NK) cells and a subset of T lymphocytes. This unconjugated IgG reagent from Antibodies.com is validated for Western Blot (WB) detection and shows reactivity against both human and mouse samples, supporting cross-species investigation of NK cell-mediated immune regulation. KIR2DL1 recognizes HLA-C allotypes carrying the C2 epitope, making it a relevant reagent for studies of NK cell inhibition, innate immunity, transplant immunology, and receptor-ligand interactions within the MHC class I pathway. Supplied as a 200 µl liquid aliquot suitable for repeated use when stored refrigerated and protected from repeated freeze-thaw cycles. Researchers apply this antibody to examine KIR expression profiles in NK cell populations, characterize inhibitory signaling through ITIM-bearing cytoplasmic tails, and explore disease contexts including viral infection, reproductive immunology, and hematological malignancies. The rabbit host enables broad secondary antibody compatibility across standard immunodetection workflows.