Anti-KIF2C Antibody

KIF2C, also known as MCAK, is a kinesin-family microtubule depolymerase essential for accurate chromosome congression and segregation during mitosis, where it corrects erroneous kinetochore-microtubule attachments and regulates spindle dynamics. This unconjugated Rabbit polyclonal antibody from Antibodies.com is raised against KIF2C and is supplied as 100 µl of ready-to-use reagent in a single vial. The reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows, giving laboratories a single primary antibody for protein-level, tissue-level, and subcellular-localization studies of the same target. Reactivity covers Human, Mouse, and Rat samples, supporting comparative work across patient-derived material and standard model systems used in cell-cycle and oncology research.

Investigators studying mitotic fidelity, aneuploidy, centromere-kinetochore behavior, spindle assembly checkpoint function, or KIF2C overexpression in tumor lines can use this reagent to track endogenous protein levels in lysates and to visualize localization in fixed cells and tissue sections. Recommended starting dilutions, blocking conditions, and antigen-retrieval parameters for each application are provided in the lot-specific datasheet shipped with the vial; aliquoting upon first use is advised to limit freeze-thaw cycles and preserve lot-to-lot consistency. For research use only.