Anti-KIF2A Antibody

Raised in rabbit and supplied as an unconjugated IgG preparation, this Antibodies.com polyclonal reagent binds the kinesin-13 family motor protein KIF2A. KIF2A is a microtubule-depolymerizing ATPase that localizes to spindle poles and centromeres during mitosis, where it destabilizes kinetochore microtubules and promotes proper chromosome congression and faithful segregation. Because altered KIF2A expression has been reported in several proliferative and tumor contexts, the reagent is frequently used in cell-cycle and cancer biology research as a probe for tracking motor-protein levels, localization, and post-translational regulation across dividing cells.

The antibody is validated for Western blot and immunohistochemistry applications on human tissue and cell samples, and it is provided in a 100 µl vial format that supports multiple staining or blotting experiments. As an unconjugated reagent, it can be paired with standard secondary antibodies for immunofluorescence, chromogenic IHC, or chemiluminescent WB detection, offering flexibility in downstream assay design for laboratories investigating mitotic machinery and chromosome stability.