Anti-Keap1 Antibody

Raised in rabbit against the Kelch-like ECH-associated protein 1 (Keap1), this polyclonal antibody from Antibodies.com enables investigation of the Nrf2-Keap1 signaling axis in human, mouse, and rat samples.

Keap1 is the cytoplasmic repressor that targets Nrf2 for Cul3-dependent ubiquitination, so measuring its abundance is a common entry point for projects on oxidative stress, xenobiotic metabolism, chemoprevention, and tumor biology. The polyclonal format broadens epitope coverage, which is helpful when probing post-translational modifications or mutant variants of the protein.

The reagent is supplied as a 100 µl vial of unconjugated antisera and is validated for western blot and ELISA workflows. The cross-species reactivity profile supports consistent comparisons between cell-line studies and primary tissue or animal model samples within a single laboratory.