Anti-KDEL Receptor 3 (L95) Antibody

Raised in rabbit against a synthetic peptide from the L95 region of human KDEL Receptor 3, this polyclonal reagent from Antibodies.com detects the Golgi-localized retrieval receptor that returns ER-resident chaperones bearing the KDEL/HDEL C-terminal motif back to the endoplasmic reticulum. Suited to Western blot and immunohistochemistry workflows, the antibody is supplied as 100 µl of IgG at 1 mg/ml in PBS, pH 7.2, with 0.05% sodium azide added as a preservative. Verified reactivity with human, mouse, and rat samples in manufacturer testing makes the reagent useful for cross-species studies of ER-Golgi trafficking, secretory pathway stress, and unfolded protein response signaling, where KDELR3 abundance tracks chaperone flux through the early secretory pathway. The unconjugated format is compatible with secondary detection chemistries of the user's choice, including HRP, alkaline phosphatase, and fluorophore-conjugated secondaries, and the rabbit host allows pairing with mouse primaries in double-label experiments. Aliquot the 1 mg/ml stock upon first thaw and store refrigerated at 4 °C in the dark to preserve activity; avoid repeated freeze-thaw cycles of the working vial.