Anti-KDEL Receptor 2 Antibody

KDEL Receptor 2 (KDELR2) is a Golgi-localized seven-transmembrane receptor that retrieves ER-resident proteins bearing a C-terminal KDEL tetrapeptide motif, playing a central role in retrograde transport from the Golgi back to the endoplasmic reticulum. This polyclonal reagent from Antibodies.com is raised in rabbit and validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows across human, mouse, and rat samples. The unconjugated format offers flexibility for pairing with user-selected secondary antibodies and detection chemistries. The 100 µl volume supports pilot studies and antibody titration experiments, and aliquoting is recommended to limit repeated freeze-thaw cycles. Polyclonal recognition of multiple epitopes enhances signal in immunofluorescence imaging of Golgi compartment markers and in immunohistochemistry of tissue sections. Recommended for research on ER-Golgi trafficking dynamics, secretory pathway homeostasis, and unfolded protein response (UPR) signaling.