Anti-KCNN3 Antibody

KCNN3 (also known as SK3 or SKCa3) encodes a small-conductance calcium-activated potassium channel subunit that contributes to the afterhyperpolarization phase of action potentials in many neurons and is implicated in smooth muscle tone regulation, hippocampal rhythmicity, and several neurological phenotypes under active study. Antibodies.com offers this affinity-purified rabbit polyclonal reagent as 100 µL of liquid (1 mg/mL) supplied in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotective stabilizer. The unconjugated antibody is raised in rabbit, validated for Western blot (WB) and immunohistochemistry (IHC), and cross-reacts with human, mouse, and rat samples, making it a practical reagent for comparative studies of channel expression across species and tissue types. Store refrigerated (typically 4 °C) with the glycerol component to keep the protein stable, and avoid repeated freeze-thaw cycles to preserve binding activity. The polyclonal format recognizes multiple epitopes on the KCNN3 protein, which is helpful when probing denatured lysates in WB and fixed tissue sections in IHC where a single monoclonal epitope may be masked.