Anti-KCNJ9 Antibody

This rabbit polyclonal Primary Antibody from Antibodies.com targets KCNJ9, also known as Kir3.3 or GIRK3, an inward-rectifier potassium channel predominantly expressed in neuronal tissue. Supplied as 50 µl of unconjugated IgG, the reagent is validated for Western blot detection of the channel in mouse and rat samples, with reactivity confirmed against both rodent species. The polyclonal host format recognizes multiple epitopes along the target, supporting consistent signal in western blot analysis of membrane-enriched lysates prepared from brain and other neuronal preparations.

KCNJ9 belongs to the GIRK channel subfamily and assembles into heteromeric complexes with related Kir3 subunits, coupling G-protein βγ signaling to potassium flux downstream of GPCR activation, including GABA-B and muscarinic pathways. Researchers investigating neuronal excitability, G-protein-coupled receptor signaling, and channel biophysics can use this antibody to probe endogenous protein levels and tissue distribution across rodent model systems. Aliquot upon first use and store refrigerated, avoiding repeated freeze-thaw cycles to preserve antibody performance. Provided in a single-use vial suitable for standard immunoblotting workflows.