Anti-KCNJ15 Antibody

This rabbit polyclonal antibody from Antibodies.com targets KCNJ15, also known as Kir4.2, an inward-rectifier potassium channel encoded on the long arm of human chromosome 21. Investigators apply this reagent in western blot workflows to probe KCNJ15 expression across human, mouse, and rat samples, supporting studies of potassium handling in renal tissue, channel localization in neural preparations, and emerging research connecting this gene to epilepsy phenotypes and to type 2 diabetes susceptibility loci.

The antibody is supplied as 100 µl of liquid at approximately 1 mg/ml, formulated in phosphate buffered saline (PBS) with 15 mM sodium azide as a preservative at roughly pH 7.2. As an unconjugated polyclonal reagent raised in rabbit hosts, it integrates into standard immunoblotting pipelines, where researchers pair it with HRP-conjugated or fluorophore-conjugated secondary antibodies matched to their chosen detection chemistry.

Handling recommendations: keep the vial refrigerated short term, aliquot on first use to limit repeated freeze-thaw cycles that degrade IgG preparations, and shield from prolonged light exposure. Each preparation is unconjugated and suited to denatured lysate conditions characteristic of SDS-PAGE separation followed by western blot transfer to nitrocellulose or PVDF membranes.