Anti-karyopherin alpha 2 Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated primary antibody from Antibodies.com targets karyopherin alpha 2, a nuclear import receptor that recognizes classical nuclear localization signals and shuttles NLS-bearing cargo proteins from the cytoplasm into the nucleus.

Validated for western blot and immunofluorescence workflows on human samples, the reagent ships as 100 µl of unconjugated antiserum suitable for chemiluminescent WB membrane detection and IF imaging paired with a researcher-selected secondary antibody.

Because karyopherin alpha 2 (also known as importin alpha 2 or KPNA2) is frequently overexpressed in proliferating tumor cells and has been investigated as a proliferation-associated antigen in cervical, breast, and lung carcinomas, this antibody is commonly used to study nuclear import mechanisms, NLS recognition biochemistry, and KPNA2 expression as a marker of cell proliferation in cancer research settings. Storage at -20 °C in aliquots is recommended for working-dilution stability across repeat experiments.