Anti-Jun (phospho T91) Antibody

This polyclonal antibody from Antibodies.com targets the Jun transcription factor (also known as c-Jun) when phosphorylated at threonine 91. Jun is a core component of the AP-1 transcription factor complex and participates in signaling cascades that govern cell proliferation, differentiation, stress response, and apoptosis. Phosphorylation at T91 is one of the regulatory modifications controlling Jun transcriptional activity and has been studied in the context of JNK pathway signaling, genotoxic stress, and oncogenic transformation.

Raised in rabbit, this unconjugated IgG reagent is supplied in a vial as 100 µl of liquid and is validated for Western blot detection of phospho-T91 Jun in human samples. Researchers use it to investigate Jun activation kinetics, upstream kinase activity (notably c-Jun N-terminal kinases), and downstream gene expression programs in cell lysates prepared from cultured mammalian cells or tissue specimens.

Aliquot on receipt and store at -20°C to limit freeze-thaw cycles, with short-term use at 4°C as needed. The reagent is intended for research use only, supporting studies in cancer biology, neurodegeneration, and cellular stress signaling where Jun phosphorylation status serves as a key biomarker of pathway activation.