Anti-JNK1 + JNK2 + JNK3 Antibody [Assigned #A11119]

Raised in rabbit as a monoclonal IgG, this unconjugated primary antibody from Antibodies.com recognizes the JNK family of stress-activated MAP kinases, detecting JNK1 (MAPK8), JNK2 (MAPK9), and JNK3 (MAPK10) in their full-length and phosphorylated states. The reagent is validated for western blot, immunofluorescence, and immunoprecipitation workflows, and it cross-reacts with human, mouse, rat, bovine, canine, monkey, and zebrafish samples, making it useful for comparative signaling studies across cell lines and primary tissues.

JNK kinases phosphorylate c-Jun and other transcription factors in response to cytokines, UV exposure, and oxidative stress, linking them to apoptosis, inflammation, and neuronal injury pathways. Supplied as 200 µl of liquid stock, the antibody pairs with anti-rabbit secondary reagents for chemiluminescent or fluorescent detection, and its monoclonal format supports reproducible lot-to-lot performance in kinase activation assays and pathway-mapping projects.