Anti-JNK1 (1A4) Antibody

The JNK1 (c-Jun N-terminal kinase 1) protein is a serine/threonine kinase in the MAPK family that mediates stress-activated signal transduction, including phosphorylation of c-Jun and other downstream transcription factors. This unconjugated mouse monoclonal antibody, clone 1A4, from Antibodies.com is supplied as a 50 µl liquid aliquot in 0.1M Tris-Glycine buffer (pH 7.4) containing 150 mM NaCl, 0.2% sodium azide as preservative, and 50% glycerol.

Validated for western blot (WB) and immunofluorescence (IF) workflows, the reagent shows confirmed reactivity against human, mouse, and rat JNK1, supporting comparative studies across cultured cell lines, primary tissues, and animal model systems. Researchers investigating JNK-dependent apoptosis, inflammatory cytokine signaling, or cellular responses to UV, oxidative, and osmotic stress commonly use this clone to detect the ~46/54 kDa JNK1 isoforms on immunoblots and in fixed-cell imaging.

For storage, keep at -20 °C in working aliquots to limit freeze-thaw cycles; the sodium azide prevents microbial contamination of the single-use vial. The unconjugated format permits direct labeling in the laboratory or pairing with a wide panel of secondary antibodies of choice for multiplex immunofluorescence and chemiluminescent detection in research-use-only protocols.