Anti-JAK1 Antibody

Target the Janus kinase 1 (JAK1) signaling protein with this rabbit polyclonal antibody, supplied as 50 µl of unconjugated antiserum for flexible assay design. Produced by Antibodies.com, this primary antibody is validated for Western blot, immunohistochemistry, and ELISA workflows across human, mouse, and rat sample types, supporting research into cytokine-receptor signal transduction through the JAK-STAT cascade. JAK1 associates with the intracellular domains of cytokine receptors such as type I interferons, gp130-utilizing receptors (IL-6 family), and class II cytokine receptors, making antibodies against it useful in studies of immune cell activation, inflammatory responses, and hematopoietic signaling. Investigators working on autoimmune disease models, cytokine storm biology, interferon pathway dissection, or kinase inhibitor screening can use this reagent to probe endogenous JAK1 levels and post-translational modifications in cell lysates and tissue sections. The polyclonal format provides multiple epitope recognition for robust signal in WB and IHC, while the unconjugated presentation allows downstream labeling with HRP, fluorophores, or biotin depending on the detection chemistry required. Aliquot upon receipt and store refrigerated; avoid repeated freeze-thaw cycles to preserve antibody activity. For research use only.