Anti-JAK1 Antibody

JAK1 (Janus Kinase 1) is a non-receptor tyrosine kinase that couples cytokine receptors to intracellular signaling cascades, most notably the JAK-STAT pathway governing immune cell differentiation, hematopoiesis, and interferon responses. This rabbit polyclonal antibody from Antibodies.com is raised against JAK1 and is supplied as 100 µl of unconjugated antiserum for use in western blot, immunohistochemistry, and ELISA workflows. Researchers studying cytokine signaling, oncology, and autoimmune disease mechanisms employ it to detect endogenous levels of the kinase across human, mouse, and rat samples. Polyclonal recognition of multiple epitopes on JAK1 makes it well suited to immunoblotting of total cell lysates and to IHC localization of the kinase in tissue sections, where it complements studies of STAT1 and STAT3 phosphorylation downstream of interferon and interleukin signaling. The unconjugated format allows flexible pairing with HRP-, biotin-, or fluorophore-conjugated secondary reagents to fit individual experimental designs.