Anti-IZUMO1 Antibody [#125]

This rat monoclonal clone (#125) targets IZUMO1, a sperm-surface immunoglobulin-type protein essential for gamete fusion during fertilization. IZUMO1 is expressed on the equatorial segment of mature spermatozoa and engages the oocyte receptor JUNO (IZUMO1R) to mediate sperm-egg membrane adhesion, a process critical to male fertility and reproductive biology research.

Supplied as a liquid IgG2a formulation in 100 µg aliquots, this unconjugated reagent from Antibodies.com supports western blot, immunoprecipitation, and immunofluorescence workflows in mouse and human samples. Store at -20°C in single-use vials; avoid repeated freeze-thaw cycles to preserve binding activity.