Anti-IVNS1ABP Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets IVNS1ABP, the Influenza Virus NS1A Binding Protein initially characterized through its interaction with the influenza A virus NS1 protein. The target has since been studied for its role in pre-mRNA splicing regulation and has emerged as a molecule of interest in oncology, with published work linking its expression to gastric cancer progression, glioma biology, and other solid tumor contexts.

Validated for Western blot and immunohistochemistry, the antibody is supplied as 50 µL per vial in IgG isotype from rabbit host. Cross-reactivity has been confirmed against human, mouse, and rat samples, supporting translational studies that span cell line panels, primary tissue specimens, and animal disease models. The unconjugated format offers flexibility to pair the antibody with HRP, biotin, fluorophore, or gold secondary detection chemistries of the end user's choice.

Typical research applications include mapping IVNS1ABP expression in tumor tissue microarrays, probing splicing-factor complexes by immunoblot, and exploring host-pathogen interactions relevant to influenza virology. Researchers frequently cite IVNS1ABP when investigating nuclear RNA processing, stress response pathways, and proliferative signaling cascades. The polyclonal format provides broader epitope coverage than monoclonal alternatives, which can be useful when probing conserved regions or post-translational modifications across orthologs.

Storage at -20 °C in working aliquots is recommended to preserve activity across multiple freeze-thaw cycles. Each lot is affinity-purified and quality-controlled.