Anti-IVD Antibody

This polyclonal reagent from Antibodies.com targets isovaleryl-CoA dehydrogenase (IVD), a mitochondrial matrix enzyme that catalyzes the third step of leucine catabolism. Generated in rabbit hosts and supplied as an unconjugated IgG preparation in a 100 µl vial, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence workflows against human samples.

Researchers investigating isovaleryl-CoA dehydrogenase deficiency and related branched-chain organic acidurias use this reagent to examine enzyme expression in patient-derived fibroblasts, hepatocytes, and archival tissue sections. It is also deployed in studies of mitochondrial bioenergetics, leucine metabolism, and the broader biology of acyl-CoA dehydrogenases, where specific detection of IVD on blots and tissue sections supports both diagnostic research and mechanistic inquiry.

For best results, aliquot upon receipt and store the vial frozen at -20 degrees C, avoiding repeated freeze-thaw cycles to preserve antibody activity. The reagent is intended for research use only.