Anti-ITIH1 Antibody

Raised in rabbit against the human Inter-alpha-Trypsin Inhibitor Heavy Chain 1 (ITIH1) target, this polyclonal IgG reagent from Antibodies.com is supplied as 50 µl of unconjugated serum and validated for Western blot (WB) workflows on human samples. ITIH1 functions as a heavy-chain constituent of circulating pre-α-inhibitor and other inter-α-trypsin inhibitor (ITI) complexes that stabilize the extracellular matrix and modulate hyaluronate organization in the pericellular space.

Independent studies have linked reduced ITIH1 expression to ovarian and other solid tumor contexts, making the antibody useful for oncology, inflammation, and matrix biology projects that probe protease-inhibitor balance, acute-phase response, or cell adhesion signaling. When paired with HRP-conjugated anti-rabbit secondary reagents, the antibody supports chemiluminescent detection on whole-cell lysates, conditioned media, and tissue homogenates prepared from human-derived material.

The product ships as a 50 µl liquid vial of polyclonal rabbit IgG, unconjugated, ready to combine with a user-supplied reporter enzyme or fluorophore. For routine use, keep the vial refrigerated; for longer-term storage, aliquot and freeze, and limit freeze-thaw cycles to preserve binding activity. Intended for research use only, in vitro laboratory applications.