Anti-ITGB3 (phospho Y773) Antibody

Phosphorylation of integrin beta-3 (ITGB3) at tyrosine 773 is a regulated modification tied to integrin activation, cell-matrix adhesion, and downstream signaling in platelets and many adherent cell types. This rabbit polyclonal reagent from Antibodies.com binds selectively to the Y773-phosphorylated form of ITGB3, allowing researchers to distinguish active signaling complexes from the unphosphorylated protein in signaling studies.

Supplied as 200 µl of unconjugated IgG in a vial, the antibody is validated for Western blot and immunohistochemistry on human and mouse samples, supporting applications in vascular biology, cancer cell adhesion, platelet aggregation, and thrombus research. The polyclonal format provides recognition of multiple epitopes surrounding the phospho-Y773 site, and the unconjugated format allows flexible pairing with HRP, fluorescent, or biotin secondary reagents of the researcher's choice.

For handling, store the vial refrigerated and protect from light; aliquot upon first use to limit freeze-thaw cycles and preserve phospho-specific binding activity across multiple experiments. The reagent is intended for research use only.