Anti-ITGB3 (phospho Y773) Antibody

Phosphorylation at tyrosine 773 of the integrin beta-3 (CD61/GPIIIa) cytoplasmic tail is a key event in outside-in integrin signaling that follows ligand engagement and Src-family kinase activation, contributing to focal adhesion turnover and cytoskeletal reorganization during cell spreading. The rabbit polyclonal antibody from Antibodies.com targets this phospho-Y773 epitope and is supplied as 100 µl of unconjugated IgG for selective detection of the phosphorylated form in human and mouse samples. Validated applications include western blot analysis of cell lysates and immunohistochemistry on tissue sections from both species. Because the antiserum recognizes only the tyrosine-773 phosphorylated beta-3 integrin, it is suited to research on platelet activation, angiogenesis, osteoclast adhesion, tumor cell invasion, and integrin signaling dynamics where phospho-specific discrimination matters. Aliquot the vial upon arrival and store frozen to preserve phospho-epitope reactivity through repeated freeze-thaw cycles.