Anti-ITGAL Antibody

Raised in rabbit against a recombinant human ITGAL immunogen and affinity-purified by immunogen chromatography, this unconjugated polyclonal reagent from Antibodies.com detects endogenous levels of total ITGAL protein. The antibody is validated for Western blot and immunohistochemistry on Human, Mouse, and Rat samples, making it useful for comparative studies of leukocyte adhesion in inflammatory and autoimmune models. Supplied at 1.0 mg/mL in 100 µl vials in phosphate-buffered saline pH 7.4 with 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, it is shipped at 4 °C and should be aliquoted and stored at -20 °C to avoid repeated freeze-thaw cycles. ITGAL (CD11a) is the alpha chain of the LFA-1 integrin that pairs with CD18 (ITGB2) to bind ICAM-1 and mediate T-cell activation and immune cell transmigration. The unconjugated format gives flexibility to pair with HRP, fluorophore, or biotin-conjugated secondary antibodies. Shipped from St. Louis, MO with a 6–9 business day lead time. For research use only.